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Edward J Perkins Selected Research

cyclonite (RDX)

1/2014MicroRNA and messenger RNA profiling reveals new biomarkers and mechanisms for RDX induced neurotoxicity.
2/2013Delayed myelosuppression with acute exposure to hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) and environmental degradation product hexahydro-1-nitroso-3,5-dinitro-1,3,5-triazine (MNX) in rats.
7/2012A systems toxicology approach to elucidate the mechanisms involved in RDX species-specific sensitivity.
1/2011Investigations of transcript expression in fathead minnow (Pimephales promelas) brain tissue reveal toxicological impacts of RDX exposure.
7/2009Neurotoxicogenomic investigations to assess mechanisms of action of the munitions constituents RDX and 2,6-DNT in Northern bobwhite (Colinus virginianus).
4/2009Global gene expression in rat brain and liver after oral exposure to the explosive hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX).
7/2007Subacute toxicity of oral 2,6-dinitrotoluene and 1,3,5-trinitro-1,3,5-triazine (RDX) exposure to the northern bobwhite (Colinus virginianus).

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Edward J Perkins Research Topics

Disease

4Anemia
12/2018 - 07/2010
4Seizures (Absence Seizure)
03/2016 - 04/2009
3Inflammation (Inflammations)
01/2014 - 12/2007
2Malaria
12/2018 - 11/2012
2Methemoglobinemia
12/2018 - 12/2007
2Infections
12/2018 - 11/2012
2Weight Loss (Weight Reduction)
03/2016 - 01/2011
2Neoplasms (Cancer)
11/2015 - 03/2014
2Emaciation
07/2009 - 10/2007
1Schizophrenia (Dementia Praecox)
12/2021
1Starvation
03/2016
1Respiratory Insufficiency (Respiratory Failure)
11/2015
1Stupor
11/2015
1Necrosis
08/2015
1Epilepsy (Aura)
01/2015
1Nervous System Diseases (Neurological Disorders)
01/2014
1Congenital Abnormalities (Deformity)
07/2012
1Acute-Phase Reaction
07/2012
1Hypoxia (Hypoxemia)
11/2010
1Lethargy
07/2009
1Hemorrhage
12/2007
1Diarrhea
10/2007
1Body Weight (Weight, Body)
07/2007

Drug/Important Bio-Agent (IBA)

7cyclonite (RDX)IBA
01/2014 - 07/2007
4Trinitrotoluene (TNT)IBA
12/2018 - 12/2007
3Proteins (Proteins, Gene)FDA Link
11/2015 - 07/2010
32,6-dinitrotoluene (DNT)IBA
07/2009 - 07/2007
2LipidsIBA
12/2018 - 07/2010
2GABA Receptors (GABA Receptor)IBA
03/2016 - 01/2015
2Biomarkers (Surrogate Marker)IBA
03/2014 - 01/2014
2Corn Oil (Oil, Corn)IBA
11/2012 - 07/2007
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
03/2016
1Co-Repressor ProteinsIBA
03/2016
1Aromatase (CYP19)IBA
11/2015
1ChloridesIBA
01/2015
1MetalsIBA
03/2014
1MicroRNAs (MicroRNA)IBA
01/2014
1Messenger RNA (mRNA)IBA
01/2014
1CholesterolIBA
11/2012
1SuspensionsIBA
11/2012
1CollagenIBA
07/2012
1MineralsIBA
07/2012
1VitaminsIBA
07/2012
1Polycyclic Aromatic Hydrocarbons (Polynuclear Aromatic Hydrocarbons)IBA
11/2010
1pyreneIBA
11/2010
1Biological ProductsIBA
11/2010
1CadmiumIBA
11/2010
1ChromiumIBA
11/2010
1HerbicidesIBA
11/2010
1Endocrine DisruptorsIBA
11/2010
1peroxisome-proliferator-activated receptor-gamma coactivator-1IBA
07/2010
1Heme (Haem)IBA
07/2010
1Glucose (Dextrose)FDA LinkGeneric
07/2010
1ProstaglandinsIBA
07/2010
1DDTIBA
07/2009

Therapy/Procedure

1Therapeutics
12/2021